Abstract:The paper discussed the capability using inverse scattering sequence to implement singular interface inversion of seismic data involving multipleinformation. Since Born-approximate singular inversive algorithm only uses the linear item of inverse scattering sequence,that adapts itself only to the inversion of th a medium having small disturbance. Using Green function theory,the paper analyzed the physical meaning of inverse scattering sequence,pointed out the wave process of inverse scattering sequence propagating to receiver points in reference medium after describing wave action on scattering points in scattering region. The resuits of singular inversion of multiple-bearing seismic model containing 6 layers (involving 5 reflectors ) showed that the method in the paper can effectively make inversion of the position of interfaces ,not only adapted to the medium having small disturbance but also adapted to the medium having large disturbance.